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The Old Endoscopy Quiz (and Answer) of the Month
October 2000

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Question:

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This lady in in an age about 70 had been treated for osteoporosis for about four months. A few weeks before this examination she had started to experience some difficulties to eat solid food, and this dysphagia progressed clearly from week to week. This is the finding in the distal oesophagus. What is the probable etiology of this ulcerated stricture?

Answer

This oesophageal injury was caused by alendronate, a drug used in the treatment of osteoporosis.

Correct answers were emailed by:

Germán Lloret-Salom, Alzira, España
Vladimir Kouzmitchev, Moscow, Russia
Michael Thompson, MD, Leawood, Kansas, USA
DOKAS STEFANOS, THESSALONIKI, GREECE
Ervin Toth, Malmoe, Sweden
HIAM MUSTAFA, KHARTOUM, SUDAN
See Ling Ling, n/a, singapore
CURT TYSK, Orebro, Sweden
Rogério Godinho, Lisboa, PORTUGAL
IGNACIO HANNA JAIRALA, GUAYAQUIL, ECUADOR
antonio orozco, guadalajara, Mexico
ME Mosese, Qwaqwa, RSA
dancho danchev, plovdiv, bulgaria
Josep Roure, Girona, Spain
Lars G Salde, Lund, Sweden
Kathy Jones, Humble, USA
ZAHREDDINE Radwan, BEYROUTH, LEBANON

Stockholm, Sweden
Marcello Orlandi, Stockholm, Sweden
Hanne Svendsen, Warsaw, Poland
waseem ahmed, rawalpindi, pakistan
Antonio Sia, Patrocinio, Brazil
Hermann Teroll, Valencia, Spain

Comments:

This type of lesion is nowadays seen very rarely, since alendronate is adminstered once weekly.

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